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Start with a virtual consultation!

Speak with a certified medical professional to receive personalized advise, discuss age-related issues and therapies and formulate a plan to improve your longevity!

Love More, Age Less

  • Promotes cellular energy production.

  • Supports DNA health and repair.

  • Required to “turn off” genes that accelerate degenerative aging processes.

  • NAD+ is a required “helper” molecule for proteins that regulate other cellular functions. 

TADALAFIL BENEFITS

Tadalafil 
Prescribed Online & Delivered to Your Door

AgelessRx provides convenient & affordable access to Tadalafil to help you perform your best. No insurance required. Our ED treatments are discreetly delivered by an accredited United States pharmacy, right to your door.

Starting at $2/pill

HSA/FSA Eligible

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IMPORTANT SAFETY INFORMATION & COMMON SIDE EFFECTS

As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours. 

Most Common Side Effects of Tadalafil

  • Headache 
  • Indigestion 
  • Back pain 
  • Muscle pain 
  • Flushing 
  • Stuffy nose 

Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur: 

  • An erection will not go away (priapism). If you have an erection that lasts longer than 4 hours, get medical help right away. If not treated right away, priapism can permanently damage the penis.
     
  • Sudden vision loss or bluing in one or both eyes. Sudden vision loss can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION).

  • Sudden hearing decrease or hearing loss. Some may also have ringing in the eyes (tinnitus) or dizziness. 

For a complete list of possible side effects, click here.

Possible Drug Interactions

Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat.

On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.

For a complete list of possible drug interactions, click here.

Other Important Safety Information 

Patients who have a condition called "left ventricular outlet obstruction" from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.

After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.

Note: All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or health care provider.

IMPORTANT SAFETY INFORMATION & COMMON SIDE EFFECTS

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Tadalafil (Daily)
Starting at $60 $42
/mo

LIMITED TIME: Free Medical Evaluation and 30% Off

Slowing aging has never been simpler

Get access to cutting edge longevity treatments without leaving the couch

Explore our treatments

Browse our offerings or tell us about your health goals. 

Pause or cancel anytime

Plus, enjoy ongoing support from our world-class care team.

Get medical review

Fill out a brief intake form and receive a response in 2-3 days.

Enjoy fast, free shipping

Orders are delivered anywhere in the US within 5-7 business days.

NAD+ can help you do more and age less.


Shown to reduce heart disease risk up to 60% by improving blood flow and circulation.1

Unlock big benefits beyond ED

Tadalafil can help promote healthy circulation and support your body’s natural defenses—so you can keep moving forward.

NAD+ can help you do more and age less.


May reduce Alzheimer’s risk up to 44% by boosting blood flow to the brain.2

NAD+ can help you do more and age less.


May reduce the risk of all-cause mortality
by up to 34%.
3

¹PubMed, 2024, ²Neurology, 2024,  ³American Journal of Medicine, 2025

Get started

Tadalafil for Longevity

In Stock

Free Shipping

Free on-demand support

Helping 200k+ people nationwide

More than symptom relief—supporting healthier years ahead for both men and women. While widely known for ED and prostate health, emerging research suggests Tadalafil may help promote:

Tadalafil (Daily)

  • 1 tab daily for consistent longevity support
  • 2.5 or 5mg daily dose, as prescribed
  • Discreet packaging
  • FREE shipping & on-demand prescriber support
  • 30% off applied at checkout

Limited time offer of 30% off first order applied automatically at checkout

Not Available in SC & ND

Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. See below for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown.

Get started

Monthly  $70 $49/month
30 daily doses | Billed & shipped monthly

Quarterly   $60 $42/month
90 daily doses | Billed & shipped quarterly

Get started

BEST DEAL

In Stock

Your monthly prescription includes: 

Compounded Semaglutide
Starting at $290/month

LIMITED TIME: Free Medical Evaluation and 30% Off

2.5mL Monthly

$185
/month

Billed every 4 weeks

Includes $50 off your first month

5mL Monthly

Billed every 4 weeks

Includes $50 off your first month

$345
/month

Helping 200k+ people nationwide

Free on-demand support

Free Shipping

Slowing aging has never been simpler

Get access to cutting edge longevity treatments without leaving the couch

Explore our treatments
Browse our offerings or tell us about your health goals. 

Pause or cancel anytime
Plus, enjoy ongoing support from our world-class care team.

Get medical review
Fill out a brief intake form and receive a response in 2-3 days.

Enjoy fast, free shipping
Orders are delivered anywhere in the US within 5-7 business days.

Unlock big benefits 
beyond ED

Tadalafil can help promote healthy circulation and support your body’s natural defenses—so you can keep moving forward.

Shown to reduce heart disease risk up to 60% by improving blood flow and circulation.¹

May reduce Alzheimer’s risk up to 44% by boosting blood flow to the brain.²

May reduce the risk of all-cause mortality by up to 34%.3

Tadalafil (Daily)

Limited time offer of 30% off first order applied automatically at checkout


Not Available in SC & ND

Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. See below for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown.

Get started

Monthly $70 $49/month 

  • 30 daily doses
  • Billed & shipped monthly
Get started

Quarterly  $60 $42/month 

  • 90 daily doses
  • Billed & shipped quarterly

Your monthly prescription includes:


  • Free & ongoing medical support
  • 1 tab daily for consistent longevity support
  • 2.5 or 5mg daily dose, as prescribed
  • Discreet packaging
  • FREE shipping & on-demand prescriber support
  • 30% off applied at checkout

BEST DEAL

In Stock

Tadalafil for Longevity

More than symptom relief—supporting healthier years ahead for both men and women. While widely known for ED and prostate health, emerging research suggests Tadalafil may help promote:

Get started


Starting at $60 $42
/mo

As we age, an enzyme called PDE5 becomes more active, narrowing blood vessels and obstructing blood flow* throughout the body and brain. In fact, cerebral blood flow can decline by about 0.3–0.5% every year.4 Tadalafil blocks PDE5, helping restore healthy circulationsupport cognitive function5, and lead to decreased risk of Alzheimer's and dementia.5

A science-backed approach

NAD+ can help you do more and age less.


As we age, an enzyme called PDE5 becomes more active, narrowing blood vessels and obstructing blood flow* throughout the body and brain. In fact, cerebral blood flow can decline by about 0.3–0.5% every year.4 Tadalafil blocks PDE5, helping restore healthy circulation, support cognitive function, and lead to decreased risk of Alzheimer's and dementia.5

A science-backed
approach

¹CPN, 2019, ²ECancer, 2018,  ³Nature, 2019, 4PLOS, 2012

¹CPN, 2019, ²ECancer, 2018,  ³Nature, 2019, 4PLOS, 2012